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Sealed Peptides MOTS-C research compound vial STATED PURITY ≥99%
Longevity

MOTS-C Research Peptide for Sale (USA)

Mitochondrial Peptide · MW: 2174.5 Da

MOTS-C lyophilized powder for laboratory research (16-residue sequence MRWQEMGYIFYPRKLR, listed MW 2174.5 Da). Orders ship from Michigan by USPS Priority Mail, usually within 1 business day of payment when the item is in stock, and ship free at $149.00+.

Mitochondria-derived peptide encoded in the 12S rRNA gene. Researched for metabolic regulation, insulin signaling, and exercise-related metabolic pathways. Stated purity ≥99%.

$64.99

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For research purposes only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.

US only · Ships within 1 business day · Discreet packaging

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Questions about this material? Contact support@sealedpeptides.com · Text us (810) 309-8278

Specifications

Stated purity≥99% (target)
Molecular Weight2174.5 Da
Molecular FormulaC101H152N28O22S2
Compound TypeMitochondrial Peptide
FormLyophilized powder
SequenceMRWQEMGYIFYPRKLR
Half-Life~2–4 hours
Storage-20°C lyophilized; 2–8°C reconstituted
ReconstitutionReconstitute with bacteriostatic water
USPS Priority Mail
Ships Within 1 Business Day
Discreet Shipping

Research Notes

  • Encoded in the 12S rRNA gene of mitochondrial DNA — a mitokine
  • Activates AMPK pathway and regulates AICAR/ZMP metabolite levels
  • Studied for insulin signaling, exercise-related pathways, and metabolic flexibility in models

Overview (Research Use Only)

MOTS-C is a mitochondrial-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. Supplied by Sealed Peptides for laboratory and research use only, it is classified as a mitokine — a signaling peptide of mitochondrial origin that acts on nuclear gene expression.

This product is not intended for human consumption, clinical administration, or any diagnostic, therapeutic, or preventive use. All handling should follow institutional laboratory policies for research chemicals.

Research context

Research has examined MOTS-C in models of metabolic regulation, insulin sensitivity, and exercise mimicry. The peptide activates the AMPK pathway and regulates AICAR/ZMP metabolite levels, with preclinical studies suggesting effects on glucose uptake and mitochondrial biogenesis. Age-related changes in circulating MOTS-C levels have been a focus of longevity research.

Findings in animal or in-vitro systems do not establish human efficacy or safety and must not be interpreted as medical claims.

Read full research overview →

Ordering & shipping

  • Ships from Michigan to US addresses only, by USPS Priority Mail with tracking, in discreet packaging.
  • Fast dispatch: in-stock orders usually ship within 1 business day after payment is confirmed.
  • Free shipping: USPS Ground Advantage is $6.99, free on orders of $75.00 or more; USPS Priority Mail is free on orders of $149.00 or more (after discounts); otherwise Priority Mail is a flat $14.99.
  • Payment: credit or debit card (including Apple Pay and Google Pay), Zelle (5% off the product subtotal) or cash at local pickup.
  • Preparing a solution? Read the reconstitution guide and storage guide, or browse all laboratory guides.
  • Volume pricing applies automatically when you order 2 or more of MOTS-C in the same size. See bulk pricing and shipping details.

For laboratory research use only. Not for human or veterinary use. Must be 21 or older.

Common questions

Where does MOTS-C ship from?

From Michigan, by USPS Priority Mail with tracking, to US addresses only.

What form is MOTS-C supplied in?

A lyophilized (freeze-dried) powder in a sealed vial.

Is MOTS-C sold for research use only?

Yes. It is a laboratory research material only and is not for human or veterinary use.

What does "research use only" mean?

This material is sold for laboratory and in-vitro research only. It is not for human or veterinary use, and we do not provide dosing guidance.

How should this vial be stored?

-20°C lyophilized; 2–8°C reconstituted

How fast does it ship?

Orders ship within 1 business day via USPS Priority Mail. Priority Mail is free on orders of $149.00 or more; otherwise it is $14.99. USPS Ground Advantage is $6.99, free on orders of $75 or more. US only.

Who do I contact with questions about this product?

Email support@sealedpeptides.com with the product name and your question (include your order number if you have one).

Related research

Background reading for working with MOTS-C in the laboratory: its research overview, definitions of terms used on this page, and tools for solution arithmetic. General education; it describes no use of this material.

More: Learn hub · glossary · printable lab sheets